小剂量多巴胺联合托拉塞米治疗老年慢性心力衰竭的疗效

发布时间:2018-06-23 来源: 幽默笑话 点击:

http://img1.qikan.com.cn/qkimages/zsyx/zsyx201812/zsyx20181253-1-l.jpg
  【摘要】 目的 研究小剂量多巴胺联合托拉塞米治疗老年慢性心力衰竭的临床效果。方法 130例
  老年慢性心力衰竭患者, 采用随机数字法分为对照组和观察组, 各65例。对照组给予呋塞米静脉注射, 观察组给予小剂量多巴胺联合托拉塞米静脉注射。对比两组患者治疗效果、不良反应发生情况及治疗前后左心功能变化情况。结果 观察组患者的总有效率98.46%(64/65)高于对照组的81.54%(53/65), 差异具有统计学意义(P<0.05)。观察组不良反应发生率3.08%(2/65)少于对照组的21.54%(14/65), 差异具有统计学意义(P<0.05)。治疗前, 两组患者的左心室射血分数(LVEF)、左心室舒张末期内径(LVEDD)水平比较差异无统计学意义(P>0.05);治疗后, 两组患者的LVEF、LVEDD水平均优于对照组, 差异具有统计学意义(P<0.05)。结论 在老年慢性心力衰竭治疗采用小剂量多巴胺联合托拉塞米具有显著效果, 能够有效改善患者心功能指标, 减少不良反应发生, 具有较高的临床推广价值。
  【关键词】 多巴胺;托拉塞米;慢性心力衰竭;不良反应;老年
  DOI:10.14163/j.cnki.11-5547/r.2018.12.053
  【Abstract】 Objective To study the clinical effect of low dose dopamine combined with torasemide in the treatment of elderly patients with chronic heart failure. Methods A total of 130 elderly patients with chronic heart failure were divided by random number table method into control group and observation group, with
  65 cases in each group. The control group received intravenous injection of furosemide, and the observation group received low dose dopamine combined with torasemide. Comparison were made on treatment effect, occurrence of adverse reactions and changes of left heart function before and after treatment between the two groups. Results The observation group had higher total effective rate as 98.46% (64/65) than 81.54% (53/65) in the control group, and the difference was statistically significant (P<0.05). The observation group had lower incidence of adverse reactions as 3.08% (2/65) than 21.54% (14/65) in the control group, and the difference was statistically significant (P<0.05). Before treatment, both groups had no statistically significant difference in left ventricular ejection fraction (LVEF) and left ventricular end diastolic diameter (LVEDD) level (P>0.05). After intervention, both groups had better LVEF and LVEDD level than the control group, and the difference was statistically significant (P<0.05). Conclusion Application of low dose dopamine combined with torasemide shows remarkable effect in the treatment of elderly patients with chronic heart failure, and it can effectively improve cardiac function indicator, reduce the incidence of adverse reactions. It contains a high clinical promotion value.
  【Key words】 Dopamine; Torasemide; Chronic heart failure; Adverse reactions; Elderly
  慢性心力衰竭是臨床内科常见疾病, 以老年人为多发群体, 多数患者由于心肌梗死、心肌病、血液流动学符合过重而导致心肌受损。病情初期阶段, 患者可出现呼吸困难、乏力或体液潴留等临床表现, 随疾病发展至晚期, 可出现心源性浮肿, 肾脏等功能则会受到不同程度损伤, 对其生活及健康状态造成影响[1-3]。目前, 临床多采用呋塞米药物治疗, 但长期使用会导致其疗效降低, 影响治疗效果。本研究选取130例老年慢性心力衰竭患者作为研究对象, 对其中65例采用小剂量多巴胺联合托拉塞米治疗取得满意效果, 现报告

相关热词搜索:多巴胺 心力衰竭 疗效 老年 治疗

版权所有 蒲公英文摘 www.zhaoqt.net