糖尿病周围神经损伤上肢受累分布特点的研究

　　[摘要]目的 探討糖尿病周围神经损伤上肢受累的分布特点。方法 选取2016年3月～2017年5月我院收治的300例糖尿病患者进行资料分析，将150例糖尿病周围神经病患者作为观察组，150例无周围神经疾病的糖尿病患者作为对照组，对所有患者进行肌电/诱发电位仪检测上肢正中神经、桡神经以及尺神经的感觉神经传导速度（SCV）、感觉神经传导波幅（SNAP）、运动神经传导速度（MCV）、符合肌肉动作电位波幅（CAMP）。比较两组患者的神经传导指标。结果 观察组患者的正中神经、桡神经、尺神经SCV、MCV均低于对照组，差异有统计学意义（P<0.05）。不同神经比较，正中神经、运动神经与感觉神经异常率高于其他神经（P<0.05）；尺神经与桡神经的感觉神经异常率以及运动神经异常率比较，差异无统计学意义（P>0.05）。同一感觉神经与运动神经比较，正中神经感觉神经异常率高于运动神经异常率，差异有统计学意义（P<0.05）；尺神经与桡神经的感觉神经以及运动神经异常率比较，差异无统计学意义（P>0.05）。结论 糖尿病周围神经病（DPN）患者的神经传导速度明显低于无周围神经疾病的传导速度，较无周围神经疾病的糖尿病患者的上肢神经以及正中神经受累也更为严重。
　　[关键词]糖尿病；正中神经；周围神经病
　　[中图分类号] R587.2 [文献标识码] A [文章编号] 1674-4721（2018）2（b）-0047-03
　　Study on distribution characteristics of upper extremities affected by diabetic peripheral nerve injury
　　HE Hui LUO Zhi-hong DENG Hong-wei
　　Department of Functionality，Yingde People′s Hospital in Guangdong Province，Yingde 513000，China
　　[Abstract]Objective To investigate the distribution characteristics of upper extremities affected by diabetic peripheral nerve injury.Methods 300 patients with diabetes treated in our hospital from March 2016 to May 2017 were selected and their data were analyzed.150 patients with diabetic peripheral neuropathy were selected as the observation group.150 diabetic patients without peripheral neuropathy were selected as the control group.All patients were examined by electromyography/evoked potentiometry for the detection of sensory nerve conduction velocity （SCV），sensory nerve conduction amplitude （SNAP），motor nerve conduction velocity （MCV），compound muscle action potential amplitude （CAMP） in the median nerve，radial nerve and ulnar nerve of upper extremities.The nerve conduction parameters were compared between the two groups.Results The SCV and MCV of median nerve，radial nerve and ulnar nerve in the observation group were lower than those in the control group，the difference was statistically significant （P<0.05）.Different nerves were compared，the abnormal rates of median nerve，motor nerve and sensory nerve were higher than those of other nerves （P<0.05）.There was no significant difference in the abnormal rates of sensory nerve and motor nerve between the ulnar nerve and radial nerve （P>0.05）.The sensory nerve，motor nerve，and median nerve were compared，and the abnormal rate of sensory nerve was higher than that of motor nerve，the difference was statistically significant （P<0.05）.There was no significant difference in the abnormal rate of sensory nerve and motor nerve between the ulnar nerve and radial nerve （P>0.05）.Conclusion The nerve conduction in the patients with diabetic peripheral neuropathy is significantly lower than that in the diabetic patients without peripheral neuropathy，and compared with the diabetic patients without peripheral neuropathy，the affected nerve of upper extremities and the affected median nerve are also the more severe.

相关热词搜索：周围神经 上肢 受累 损伤 糖尿病