洗涤红细胞对反复输注红细胞患者输血效果的影响

　　[摘要]目的 探讨反复输注红细胞患者采用洗涤红细胞输血的临床效果。方法 选择2015年6月～2017年6月我院收治的134例反复输血患者，随机分为对照组和研究组，每组67例。对照组患者输注去白细胞红细胞，研究组患者输注洗涤红细胞悬液，比较两组患者的输血效果及不良反应发生情况。结果 两组输血前血红蛋白（Hb）、紅细胞（RBC）、白细胞（WBC）及血小板（PLT）水平比较，差异无统计学意义（P>0.05），输血后Hb及RBC水平均较输血前提高（P<0.05），研究组输血后Hb及RBC水平高于对照组（P<0.05）。研究组Hb及WBC提高值高于对照组，差异均有统计学意义（P<0.05），两组输血前后WBC及PLT计数比较，差异无统计学意义（P>0.05），研究组输血有效率为98.5%，高于对照组的85.4%（P<0.05）。两组患者输血不良反应发生率差异无统计学意义（P>0.05）。结论 洗涤红细胞能够改善反复输血患者的红细胞输注效果，提高输血有效率。
　　[关键词]洗涤红细胞；去白细胞红细胞；反复输血；血红蛋白；红细胞计数
　　[中图分类号] R457.13 [文献标识码] A [文章编号] 1674-4721（2018）2（b）-0032-03
　　Influence of washed red blood cells on blood transfusion effect in patients with multiple red blood cells transfusion
　　WANG Yan-chun
　　Department of Transfusion，Longgang Central Hospital of Shenzhen City，Guangdong Province，Shenzhen 518172，China
　　[Abstract]Objective To investigate clinical effect of washed red blood cells （WRBC） transfusion in patients with multiple red blood cells transfusion.Methods 134 cases of patients with multiple red blood cells transfusion from June 2015 to June 2017 were randomly divided into control group and research group，67 cases in each group，and leukocyte-depleted red blood cells （LDRC） were transfused in control group，and WRBC was transfused in research group.And transfusion effect and adverse reaction were tested between control group and research group.Results Levels of Hb，RBC，WBC and PLT were no significant difference before blood transfusion between the two groups （P>0.05）.The level of Hb and RBC after transfusion were higher than those before transfusion in every group （P<0.05），and level of Hb and RBC in research group were higher than that in control group after transfusion （P<0.05）.Increasing of Hb and RBC was higher in research group than that in control group（P<0.05），WBC and PLT count had no significant difference between the two groups before and after blood transfusion（P>0.05），effective rate of blood transfusion was 98.5% in research group than 85.4% in control group，and effective rate of blood transfusion was higher in research groups than that in control groups（P<0.05），incidence rate of adverse transfusion reactions was no significant difference in two groups （P>0.05）.Conclusion WRBC can improve effect of red blood cells transfusion in patients with repeated blood transfusion，and improve efficiency of blood transfusion.
　　[Key words]Washed red blood cells；Leukocyte removed erythrocytes；Repeated blood transfusion；Hemoglobin；Red blood cell count

相关热词搜索：红细胞 输血 洗涤 患者 反复