血浆白蛋白Alb及血红蛋白Hb水平与重型颅脑损伤患者预后的相关性

发布时间:2018-06-24 来源: 短文摘抄 点击:


  [摘要] 目的 探讨重型颅脑损伤(STBI)患者血浆白蛋白(Alb)及血红蛋白(Hb)水平与预后的相关性。方法 方便选取2016年5月—2017年4月该院ICU收治的64例STBI患者为研究对象,依治疗方式不同将入选病例分为两组。对照组32例,患者入院后立即给予及时正确地急救处理、依指征行脑外科手术及非手术治疗;实验组32例,患者在对照组治疗基础上输注人血白蛋白和悬浮红细胞以维持正常Alb及Hb水平。记录两组STBI患者治疗期间血浆Alb水平、Hb水平及格拉斯哥昏迷评分(GCS),对比观察Alb及Hb水平与STBI患者预后的相关性。结果 实验组生存率90.6%,死亡率9.4%,Alb(34.6±2.8)g/L,Hb(99.3±6.4)g/L,各项指标均优于对照组(P<0.05),Alb<30 g/L、Hb<90 g/L是STBI患者死亡危险因素。结论 血浆白蛋白及血红蛋白水平与重型颅脑损伤患者预后存在密切关联,维持Alb≥30 g/L、Hb≥90 g/L对STBI患者预后具有重要意义。
  [关键词] 重型颅脑损伤;血浆白蛋白;血红蛋白;预后
  [中图分类号] R651 [文献标识码] A [文章编号] 1674-0742(2018)01(c)-0031-03
  [Abstract] Objective This paper tries to investigate the correlation between serum albumin (Alb) and hemoglobin (HB) level in patients with severe craniocerebral injury (STBI). Methods 64 cases of STBI patients in the hospital from May 2016 to March 2017 were convenient selected and were divided into two groups according to the treatment methods. The control group of 32 cases, patients were given prompt and proper first aid treatment immediately after admission, according to the indications of brain surgery and non-surgical treatment; experimental group of 32 patients, based on the control group added the infusion of human serum albumin and suspended red blood cells to maintain normal Alb and Hb Level. The levels of Alb, Hb and Glasgow Coma Scale(GCS) were recorded during treatment in two groups of STBI patients. The correlation between Alb and Hb levels and the prognosis of STBI patients was compared. Results The survival rate of experimental group was 90.6%, mortality rate was 9.4%, Alb(34.6±2.8)g/L, Hb (99.3±6.4)g/L, significantly better than the control group(P<0.05), Alb<30 g/L, Hb<90 g/L as the death risk factors of STBI. Conclusion The plasma albumin and hemoglobin level are closely correlated with the prognosis of severe craniocerebral injury, and to maintain Alb≥30 g/L and HB≥90 g/L is important to the prognosis of patients.
  [Key words] Severe craniocerebral injury; Plasma albumin; Hemoglobin; Prognosis
  Alb是血漿中最主要的功能性蛋白,是反应机体营养状态的重要指标,而Hb是负责运载氧的重要蛋白,其功能性与患者机体损伤存在密切相关性,故维持STBI患者正常血浆Alb及Hb水平对改善预后具有重要意义[1]。该院ICU近年来STBI患者在常规治疗基础上加用液体疗法以长期稳定维持STBI患者血浆Alb及Hb水平取得良好治疗效果,文章现以2016年5月—2017年4月该院ICU收治的64例STBI患者为例,对Alb及Hb水平与STBI患者预后的相关性进行分析和探讨,具体报道如下。
  1 资料与方法
  1.1 一般资料
  以该院ICU收治的64例STBI患者为研究对象,依治疗方式不同将入选病例分为两组。实验组(32例):男24例,女8例;年龄(47.9±5.8)岁;入院时GCS(6.1±0.7)分;APACHEII评分(24.9±3.2)分。对照组(32例):男25例,女7例;年龄(47.5±6.3)岁;入院时GCS(6.2±0.5)分;APACHEII评分(25.1±2.7)分。两组一般资料差异无统计学意义(P>0.05),具有可比性。

相关热词搜索:白蛋白 颅脑 血红蛋白 预后 血浆

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