浅析血清降钙素原、C反应蛋白在支气管哮喘合并感染中的检测诊断价值

发布时间:2018-06-24 来源: 短文摘抄 点击:


  【摘要】 目的:探讨血清降钙素原(PCT)、C反应蛋白(CRP)在支气管哮喘(BA)合并感染中的诊断价值。方法:选取笔者所在医院自2015年5月-2016年5月收治的110例支气管哮喘患者作为试验对象,依据是否合并感染将其分成三组,单纯哮喘组32例,合并细菌感染患者48例,合并病毒感染30例,分别测定三组患者血清中PCT、CRP水平,比较该两项指标在支气管哮喘合并感染诊断中的临床价值。结果:哮喘合并细菌感染患者血液中PCT、CRP水平高于合并病毒感染患者,哮喘合并病毒感染患者PCT、CRP水平高于单纯哮喘患者,数据对比差异有统计学意义(P<0.05);哮喘合并细菌感染患者PCT阳性率、CRP阳性率显著高于其他两类,数据对比差异有统计学意义(P<0.05)。结论:通过测定支气管哮喘患者血压前中PCT、CRP水平能够准确鉴别是否合并细菌感染,为制定治疗方案提供指导。
  【关键词】 支气管哮喘; 降钙素原; C反应蛋白; 阳性率
  doi:10.14033/j.cnki.cfmr.2018.5.038 文献标识码 B 文章编号 1674-6805(2018)05-0075-02
  【Abstract】 Objective:To investigate the serum calcitonin(PCT) and c-reactive protein(CRP) in bronchial asthma(BA) co-infection of diagnostic value.Method:From May 2015 to May 2016,in our hospital of 110 patients with bronchial asthma were selected as the experimental object,on the basis of whether amalgamative infection they were divided into 3 groups,group of 32 cases of simple asthma,merger of 48 patients with bacterial infections,30 cases of virus infection,three group patients were determined in serum PCT and CRP level, the two indicators in the diagnosis of bronchial asthma combined infection clinical value were compare.Result:Patients with asthma complicated by bacterial infection in the blood of PCT and CRP levels higher than the merge infection group,asthma merge infection group of PCT and CRP levels were higher than the simple asthma group,data comparison differences were statistically significant(P<0.05).Positive predictive value of PCT and CRP in patients with asthma complicated by bacterial infection group were significantly higher than other two groups,the data contrast differences were statistically significant(P<0.05).Conclusion:The determination of PCT and CRP in bronchial asthma patients blood pressure before level can accurately identify whether merger bacterial infection,to provide guidance for treatment.
  【Key words】 Bronchial asthma; Calcitonin original; C-reactive protein; Positive rate
  First-author’s address:The Second Hospital of Longyan City,Longyan 364000,China
  支氣管哮喘(bronchial asthma,BA)是由多种细胞和细胞组分参与气道慢性验证性疾病,患者主要的症状为喘息、胸闷、咳嗽,尤以晚间发作,影响患者的正常休息。BA发作时部分患者会并发呼吸道感染、细菌感染和病毒感染,在治疗用药上有较大差异,因此为了制定针对性的治疗方案,需要对患者是否存在合并症进行鉴别诊断[1-2]。PCT和CRP均为急性细菌炎性感染的诊断和监测指标,本文则主要分析该两项指标在BA合并呼吸道感染中鉴别诊断价值,现将研究结果报告如下。
  1 资料与方法
  1.1 一般资料
  选取笔者所在医院2015年5月-2016年5月收治的110例支气管哮喘患者作为试验对象,依据是否合并感染将其分成三组,单纯哮喘组32例,男女20∶12,年龄23~67岁,平均(41.3±2.4)岁;合并细菌感染患者48例,男女比例为30∶28,年龄26~70岁,平均(40.8±2.5)岁;合并病毒感染30例,男女比例为18∶12,年龄27~66岁,平均(41.2±2.2)岁,三类患者的男女比例、平均年龄等一般资料比较差异无统计学意义(P>0.05)。

相关热词搜索:支气管哮喘 血清 浅析 合并 蛋白

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